Earlsdon Pharmacy

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£

Elleste Duet

 
Maximum Quantity Allowed:
1 mg
3 x 28
£

Elleste Duet tablets are a combination form of hormone replacement therapy (HRT). They are used in the treatment of menopause symptoms. It has 2 active ingredients, which act as an emulation of the two female sex hormones: a synthetic version of progestogen (norethisterone) and a natural version of oestrogen (estradiol).

Product supplied may be from a different manufacturer

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Description

What is it?

Elleste Duet is a form of combined HRT used to alleviate symptoms of menopause in women who have not had a hysterectomy. It contains two hormones: estradiol (a form of oestrogen) and norethisterone (a progestogen). The combination of these hormones helps to balance the body's hormone levels, thereby reducing common menopausal symptoms such as hot flushes, night sweats, mood changes, and vaginal dryness.

As a cyclical treatment, the first 16 tablets in a cycle in the Elleste Duet pack contain estradiol only. The final 12 tablets consist of a combination of norethisterone and estradiol. This reduces the risk of cancer and causes a regular period. There are three types of Elleste Duet. The 16 white tablets consist of 1mg estradiol in the 1mg pack; the 12 green tablets contain 1mg estradiol and 1mg norethisterone. The 16 orange tablets comprise 2mg estradiol in the 2mg pack; the 12 grey tablets comprise 1mg norethisterone and 2mg estradiol. Elleste Duet Conti tablets contain 2mg estradiol and 1mg norethisterone in all the white tablets.

How Does it Work?

Elleste Duet works by supplementing the body's natural hormone levels, which decrease during menopause. Estradiol helps replace the oestrogen, reducing symptoms associated with menopause, while norethisterone provides progestogen to protect the lining of the uterus from the potential adverse effects of oestrogen-only HRT

Warnings

It is not suitable to take Elleste Duet if you:

  • Have had breast cancer before
  • May have cancer that is sensitive to oestrogen (inclusive of uterine cancer)
  • Have endometrial hyperplasia that's not yet treated
  • Have had a blood clot before or are suffering from a blood clotting disorder
  • Have recently had a stroke or heart attack
  • Have unexplained vaginal bleeding
  • Suffering from porphyria
  • Have a history of liver disease
  • Are pregnant or breastfeeding
  • Are allergic to any of the ingredients in Elleste Duet Conti

If you've had any of the following conditions before, tell your medical officer before you take Elleste Duet:

  • Fibroids
  • Impaired liver function
  • Uterine problems including endometrial hyperplasia or endometriosis
  • Circulation problems
  • High risk of blood clots
  • Diabetes
  • High blood pressure
  • Migraine
  • Gallstones
  • An autoimmune disorder
  • Asthma
  • Epilepsy
  • A history of severe allergic reactions
  • Fluid retention
  • High-fat levels in the blood
  • Obesity
  • Otosclerosis (a hereditary ear disorder)
  • A family history of breast cancer or any other oestrogen-sensitive cancer.

Directions

Follow the guidance of your healthcare provider and read the instructions before using Elleste Duet.

  • Elleste Duet should be taken for 28 days.
  • If possible, you should start the medication on the first day of your monthly period.
  • You can find information on which tablet to take next on the pill strip.
  • Upon finishing a pack, start a new one the next day.
  • Take the medicine at the same time each day, as indicated in the directions on the pack.
  • Swallow the whole tablet with water. You can do this with or without food.

Ingredients

The active ingredients found in Elleste Duet include Estradiol (as hemihydrate) and norethisterone acetate (combined tablets only). 

Elleste Duet tablets comprise the inactive ingredients lactose monohydrate, maize starch, povidone, talc, magnesium, stearate, macrogol 400 and hypromellose (E464).

Side Effects

Not everybody experiences side effects after taking Elleste Duet, nevertheless, if they do, they can include:

  • anxiety
  • nausea
  • headache
  • stomach cramps
  • breast tenderness
  • change in libido
  • skin irritation
  • rash

More serious side effects include:

  • dizziness
  • insomnia
  • breakthrough bleeding
  • diarrhoea
  • indigestion
  • acne
  • weight gain
  • back pain
  • discharge from the vagina
  • fluid retention
  • womb spasms
  • infection

Seek medical attention if the side effects become persistent or serious.