Earlsdon Pharmacy

19-21 Earlsdon St, Earlsdon, Coventry, CV5 6EP

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£

Allopurinol Tablets

 
Maximum Quantity Allowed:
300mg
28
£

Allopurinol tablets are used in the treatment of gout and specific types of kidney stones. It can also be used in the prevention of increased uric acid levels mostly in patients undergoing cancer chemotherapy. Uric acid levels in patients receiving chemotherapy usually increase because of the release of the uric acid as a result of the cancer cells that are dying. Allopurinol reduces the amount of uric acid your body produces. High levels of uric acid can lead to gout and kidney issues.

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Description

What is Allopurinol Tablet?

llopurinol is primarily used to lower uric acid levels in the blood and is commonly prescribed to prevent gout attacks and treat kidney stones. It works by reducing the production of uric acid, thereby preventing the formation of uric acid crystals in joints that lead to gout symptoms. It is also sometimes prescribed to reduce uric acid levels in patients undergoing certain cancer treatments​

 

How Does Allopurinol Work?

Every day the human body naturally produces uric acid during the breakdown of chemicals known as purines that are found in certain food and drink substances. The by-product then dissolves in the blood and exits the body through urine. However, there are instances when the body produces too much uric acid for the kidneys to handle. As a result, the uric acid forms crystals that accumulate in joints causing gout, a form of inflammatory arthritis that is extremely painful. Allopurinol belongs to a group of medications known as Xanthine Oxidase Inhibitors that work by blocking the Xanthine Oxidase enzyme that is responsible for the production of uric acid. lowering the levels of uric acid in the urine and bloodstream. Elevated uric acid can lead to gout, where sharp uric acid crystals form around the joints, causing pain and inflammation. Regular use of allopurinol can reduce the frequency of gout attacks and prevent joint damage​

Warnings

  • Allopurinol is not effective for acute gout attacks.
  • Use caution if taking antibiotics, aspirin, diuretics (e.g., furosemide), or ACE inhibitors (e.g., enalapril, ramipril), as these can interact with allopurinol.
  • Side effects may include skin rash, an increase in thyroid-stimulating hormone, liver problems, and issues with white blood cells.
  • Inform your doctor of any underlying medical conditions you may have.
  • Inform your doctor of any allergic reactions you suffer.
  • Inform your doctor of any past or present prescription medication you are using.
  • Inform your doctor of your pregnancy or breastfeeding status.
  • Do not use Allopurinol without your doctor's approval if you have kidney disease.
  • Do not administer this medication to a child without your doctor's approval.
  • Do not share your medication with others even if they have similar symptoms.

Directions

Allopurinol is taken orally, usually once a day, ideally after food to minimize side effects such as nausea. If on a high dose, your doctor may recommend splitting the dose and taking it twice a day. It is important to drink plenty of fluids (2 to 3 liters daily) while on this medication. The starting dose is often 100mg daily, which may be adjusted based on uric acid levels monitored by blood tests. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one​

  • Take the tablet once a day, especially after meals.
  • Swallow the tablet with plenty of water to help in getting rid of excess uric acid in the kidney.
  • Follow the dosage and duration instructed by your doctor to get the most benefit out of the medication.
  • Store it at room temperature away from heat and moisture.

Ingredients

The active ingredient is in each tablet is allopurinol 300 mg. The inactive ingredients are povidone, lactose monohydrate, maize starch, and magnesium stearate.

Side Effects

Common side effects include skin rash and an increase in thyroid-stimulating hormone levels. Other side effects include:

  • Fever
  • Vomiting
  • Nausea
  • Stomach pain
  • Joint pain
  • Nosebleeds
  • Loss of taste

Rare but serious side effects can involve skin problems, liver issues, or changes in blood cell counts. If you experience any severe reactions, such as skin rash or other skin-related issues, seek medical advice immediatelyHeadaches